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Journal of Medical Sciences

Year: 2006 | Volume: 6 | Issue: 2 | Page No.: 296-299
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Authors

Shahraki Mohammad Reza

M.J. Palan

Keywords

Research Article

Effect of Aluminium on Testosterone Hormones in Male Rat

Shahraki Mohammad Reza
Department of Physiology, Medical School, Zahedan University of Medical Science, Zahedan, Iran
M.J. Palan
Department of English, Zahedan University of Medical Sciences, Zahedan, Iran
This experiment was performed to study the effect of aluminum on FSH, LH and Testosterone hormones in male rat. The experiment was performed on two groups of male rats; test group received 50 mg kg-1 aluminium chloride (ip) for 20 days. Control group received the same volume phosphate buffer at this period. At the end of experiment, animals were anesthetized with Nesdonal (Sodium thiopental) over dose and sacrificed blood samples were collected and the hormones FSH, LH, Testosterone were measured by RI method. Results showed that LH and Testosterone decreased significantly in the test group compared with that of control group. But the FSH value did not change. These results indicated that aluminium injection in rats could have affect on some of sex hormones. Further studies will probably show the exact mechanism of aluminium ion on these hormones (FSH, LH and Testosterone).
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