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Journal of Medical Sciences
  Year: 2005 | Volume: 5 | Issue: 1 | Page No.: 43-46
DOI: 10.3923/jms.2005.43.46
 
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Screening for Anti-angiogenic Activity in Shiitake Mushroom (Lentinus edodes Berk) Extracts

Custer C. Deocaris, Ma. Consolacion P. de Castro, Angel T. Oabel, Elisa L. Co and Elmer-Rico E. Mojica

Abstract:
The formation of new blood vessel from pre-existing vessels or angiogenesis is an important phenomenon in the pathology of solid tumor growth and metastasis. We found that chloroform extracts from Lentinus edodes (Berk.) Sing., an edible mushroom reported to demonstrate anti-tumor and immunomodulatory activities inhibited heparin-induced angiogenesis on chick chorioallantoic membrane. Methanol and hexane fractions appeared to have no anti-angiogenic activity. This study holds promise for the potential use of this mushroom as a dietary supplement for the management of various angiogenic-related diseases, especially cancer.
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How to cite this article:

Custer C. Deocaris, Ma. Consolacion P. de Castro, Angel T. Oabel, Elisa L. Co and Elmer-Rico E. Mojica, 2005. Screening for Anti-angiogenic Activity in Shiitake Mushroom (Lentinus edodes Berk) Extracts. Journal of Medical Sciences, 5: 43-46.

DOI: 10.3923/jms.2005.43.46

URL: https://scialert.net/abstract/?doi=jms.2005.43.46

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