Skin Lesions Induced by Sodium Lauryl Sulfate (SLS) in Rabbits

Research Article

Skin Lesions Induced by Sodium Lauryl Sulfate (SLS) in Rabbits

Mohammad. A.M. Wadaan and Mohammad Mubarak

The objective of this experimental study was to elucidate the damaging effect of sodium lauryl sulfate on the skin of rabbits. Ten adult domestic rabbits (5 males, 5 females) maintained at Animal house, were used. The animals were exposed to 5% solution of sodium lauryl sulfate, by brushing on the back region, for 8 weeks (between October and December 2004). All exposed rabbits developed wide area of allopacia (hair loss) and frequent skin erosions. The affected skin was dried and wrinkled. The animals were depressed and markedly emaciated. The clinical signs commenced with the onset of the skin lesions. It was concluded that sodium lauryl sulfate is a skin irritant and can provoke skin lesions in the form of eczyma and dermatitis.

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Mohammad. A.M. Wadaan and Mohammad Mubarak, 2005. Skin Lesions Induced by Sodium Lauryl Sulfate (SLS) in Rabbits. Journal of Medical Sciences, 5: 320-323.

DOI: 10.3923/jms.2005.320.323

URL: https://scialert.net/abstract/?doi=jms.2005.320.323

Journal of Medical Sciences

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Mohammad. A.M. Wadaan

Mohammad Mubarak

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Research Article

Skin Lesions Induced by Sodium Lauryl Sulfate (SLS) in Rabbits

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