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Journal of Medical Sciences
  Year: 2005 | Volume: 5 | Issue: 3 | Page No.: 222-227
DOI: 10.3923/jms.2005.222.227
 
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Morphological Evidence of Apoptosis in Hepatocytes of Rats (Rattus norvegicus) Exposed to Arabian Incense

Saud A. Alarifi

Abstract:
Hepatocytes of rat exposed to Arabian incense revealed morphological evidence of apoptosis in their nuclei. Irregularity of the nuclear membrane was probably the initial morphological alteration. Evident chromatin condensation was the following nuclear change. Nuclear fragmentation was the subsequent nuclear apoptotic change. Each nuclear fragment was delimited with intact membrane. No evidence of chromatin lysis was noticed in the altered nuclei. Markedly shrunken nuclei with condensed chromatin were also discerned. Cytoplasmic organelles of hepatocytes with apoptotic nuclei revealed no sign of deterioration. Kupffer cells in the vicinity of the apoptotic nuclei were hypertrophied and proliferated.
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How to cite this article:

Saud A. Alarifi , 2005. Morphological Evidence of Apoptosis in Hepatocytes of Rats (Rattus norvegicus) Exposed to Arabian Incense. Journal of Medical Sciences, 5: 222-227.

DOI: 10.3923/jms.2005.222.227

URL: https://scialert.net/abstract/?doi=jms.2005.222.227

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