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Journal of Medical Sciences
  Year: 2004 | Volume: 4 | Issue: 2 | Page No.: 124-127
DOI: 10.3923/jms.2004.124.127
 
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Antibacterial and Antifungal Activity of 2-oxo Benzylidine (3-oxo Aniline) Cu (II)-ethylidinediamine

M. Asad-Ud-Daula, J.A. Khanam and A.Y.K.M. Masud Rana

Abstract:
Antibacterial and antifungal activity of 2-oxo benzylidine (3-oxo aniline) Cu (II)-ethylindiamine has been tested against a number of pathogenic bacteria and fungus with different doses. At dose 25 μg disc-1 the compound showed 6-13 mm diameter zone of inhibition against all of the tested bacteria which was found to be larger range as compared to cotrimoxazole (15-29 mm) at the same dose. Minimum inhibitory concentration was withinin the range of 64-128 μg ml-1 against all of the tested bacteria. The compound showed 0-13 mm diameter zone of inhibition against all of the tested fungus at dose 45 μg disc-1 which was found to be larger range as compared with nystatin. The brine shrimp lethality of the compound was found to be 5.23 μg ml-1 which shows a pronounced cytotoxic effect.
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How to cite this article:

M. Asad-Ud-Daula, J.A. Khanam and A.Y.K.M. Masud Rana , 2004. Antibacterial and Antifungal Activity of 2-oxo Benzylidine (3-oxo Aniline) Cu (II)-ethylidinediamine. Journal of Medical Sciences, 4: 124-127.

DOI: 10.3923/jms.2004.124.127

URL: https://scialert.net/abstract/?doi=jms.2004.124.127

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