Anti-stress Activity of Mitragyna africanus (Willd), Stembark Extract


	Journal of Medical Sciences
	Year: 2001 \| Volume: 1 \| Issue: 3 \| Page No.: 105-107 DOI: 10.3923/jms.2001.105.107

Anti-stress Activity of Mitragyna africanus (Willd), Stembark Extract

B. M. Aji , K. D. Effraim and P. A. Onyeyili

Abstract: The acute toxicity and the effect of Mitragyna africanus stembark extract of methanol (CH₃OH) on stress were investigated in rats, using its effect on pentyleneterazole induced convulsions and its muscle relaxant effect. The extract did not produce any death in the treated rats even at the highest dose (6400mg kg^-1) used. It did not protect rats treated with convulsive doses of pentylenetetrazol (100mg kg^-1) but increased the period of onset of convulsions and decreased the number of spasms. It also showed significant (p<0.05) muscle relaxant effect

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How to cite this article:

B. M. Aji , K. D. Effraim and P. A. Onyeyili , 2001. Anti-stress Activity of Mitragyna africanus (Willd), Stembark Extract. Journal of Medical Sciences, 1: 105-107.

DOI: 10.3923/jms.2001.105.107

URL: https://scialert.net/abstract/?doi=jms.2001.105.107

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