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Research Journal of Microbiology
  Year: 2009 | Volume: 4 | Issue: 10 | Page No.: 366-369
DOI: 10.3923/jm.2009.366.369
In vitro Activity of Some Antimicrobial Agents against Staphylococcus aureus and Methicillin-Resistant Staphylococcus aureus in Khartoum, Sudan
H.A. Saeed and W.B. Ahmed

Abstract:
Staphylococcus aureus is a causative agent of many types of diseases throughout the world. Patients hospitalized for long period of time usually are predisposed to infection by methicillin resistant S. aureus (MRSA). The objectives of the present study were to evaluate the efficacy of some antimicrobial agents against S. aureus and MRSA and to select the most effective antibiotic. Clinical specimens were collected from patients with wounds and/or urinary tract infections. The specimens were proceeded for isolation of the pathogens. Identification was done by conventional methods. Antimicrobial sensitivity test was carried out using modified Kirby-Bauer Disc Diffusion Technique in accordance with National Committee on Clinical Laboratory Standards (NCCLS). Of 163 S. aureus recovered, 15 (9.2%) isolates were MRSA. The most effective antimicrobial agent against both S. aureus and MRSA was vancomycin (99%). The activity of the rest antimicrobial agents was cephalexin, 92%, methicillin, 90%, cloxacillin 33%, penicillin 14% and amoxicillin 10%. It is concluded that vancomycin may be an alternative antibiotic for patients with wound and/or urinary tract infections caused by S. aureus or MRSA.
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How to cite this article:

H.A. Saeed and W.B. Ahmed, 2009. In vitro Activity of Some Antimicrobial Agents against Staphylococcus aureus and Methicillin-Resistant Staphylococcus aureus in Khartoum, Sudan. Research Journal of Microbiology, 4: 366-369.

DOI: 10.3923/jm.2009.366.369

URL: https://scialert.net/abstract/?doi=jm.2009.366.369

 
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