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Research Journal of Microbiology
  Year: 2008 | Volume: 3 | Issue: 9 | Page No.: 588-594
DOI: 10.3923/jm.2008.588.594
Anti-Viral Activity of Cissus repanda Vahl. Plant Extract on Herpes Simplex Virus
Jiraporn Nikomtat, Narumol Thongwai, Saisamorn Lumyong and Yingmanee Tragoolpua

Abstract:
The effect of Cissus repanda Vahl. plant extract on herpes simplex virus type 1 and type 2 was investigated in this study. The cytotoxicity of dichloromethane and methanol extracts of C. repanda on GMK cells was determined by MTT assay. Non toxic concentrations were used in the study. Methanol extracts of C. repanda showed higher anti-HSV efficacy than dichloromethane extracts, by plaque reduction assay, although, HSV particles were directly inhibited by both extracts. Inhibition of HSV attachment, penetration and replication were also observed, after treatment of HSV with C. repanda extracts. The most affected stage was the attachment period. Moreover, C. repanda extracts inhibited replication of HSV-2 more than HSV-1.
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How to cite this article:

Jiraporn Nikomtat, Narumol Thongwai, Saisamorn Lumyong and Yingmanee Tragoolpua, 2008. Anti-Viral Activity of Cissus repanda Vahl. Plant Extract on Herpes Simplex Virus. Research Journal of Microbiology, 3: 588-594.

DOI: 10.3923/jm.2008.588.594

URL: https://scialert.net/abstract/?doi=jm.2008.588.594

 
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