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Research Journal of Microbiology
  Year: 2007 | Volume: 2 | Issue: 4 | Page No.: 369-374
DOI: 10.3923/jm.2007.369.374
 
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In vitro Efficacy of Flavonoids from Eugenia jambolana Seeds Against ESβL-Producing Multidrug-Resistant Enteric Bacteria

R. Jamine , P. Daisy and B.N. Selvakumarb

Abstract:
Methanol extracts of Eugenia jambolana seeds (Myrtaceae), used as a traditional folklore medicine, showed inhibitory effects against the growth of a few multidrug-resistant extended spectrum beta lactamase (ESβL) producing gram-negative bacteria. Bioactivity guided fractionation yielded several fractions. One active flavonoid-containing fraction had a Minimum Inhibitory Concentration (MIC) of 7.9 to 1000 μg mL-1. The strong in vitro antibacterial activity of flavonoid derivatives against ESβL producing gram-negative bacteria suggests the compounds might find wide pharmaceutical use.
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How to cite this article:

R. Jamine , P. Daisy and B.N. Selvakumarb , 2007. In vitro Efficacy of Flavonoids from Eugenia jambolana Seeds Against ESβL-Producing Multidrug-Resistant Enteric Bacteria . Research Journal of Microbiology, 2: 369-374.

DOI: 10.3923/jm.2007.369.374

URL: https://scialert.net/abstract/?doi=jm.2007.369.374

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