The present study was attempted on the physico chemical variability of two different environs along Parangipettai and Cuddalore coastal and estuarine waters of the Bay of Bengal. Comparative study was carried out to examine the level of contaminants affecting the coastal and estuarine environment namely Nitrite, Inorganic phosphate, Ammonia and other physico-chemical parameters. Distribution of nutrients has exhibited considerable seasonal and spatial variations. Station 3 and 4 (Cuddalore coast and Uppanar Estuary) registered higher concentration of nutrients than station 1 and 2 (Vellar estuary and Parangipettai coast).