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Journal of Biological Sciences

Year: 2017 | Volume: 17 | Issue: 7 | Page No.: 312-319
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Authors

Yusr Mohamed Ibrahim Kazem

Yusr Mohamed Ibrahim Kazem

Maha Abdel-Moaty

Maha Abdel-Moaty

Salwa Mostafa El Shebini

Salwa Mostafa El Shebini

Nihad Hassan Ahmed

Nihad Hassan Ahmed

Suzanne Fouad

Salwa Tawfic Tapozada

Salwa Tawfic Tapozada

Keywords

Background and Objective: Constipation is more prevalent in obese population. Chronic constipation affects cognitive functions and mood through different mode of actions. In this clinical trial, the effect of chronic constipation and oxidative stress was studied on cognitive functions and mood in obese women and the impact of diet modification and fennel (Foeniculum vulgare) supplementation on them. Materials and Methods: One hundred and thirty women participated as volunteers, 55 obese women (group A) followed a low caloric balanced diet accompanied by supplement made from whole wheat flour mixed with 10% fennel powder, 45 obese women (group B) followed the same low caloric balanced diet only and 30 normal weight women (group C, control group) followed their own regular diet without any alterations. Two tailed student t-test was used to compare the two groups. Correlation between the different parameters was tested by Pearson test. p<0.05 were considered statistically significant. Results: Obese patients have higher incidence of constipation, which in turn affects mood, cognitive function and antioxidant activity negatively. Conclusion: Using balanced low caloric diet rich in fresh fruits and vegetables with fennel (Foeniculum vulgare) supplementation treated constipation and improved the antioxidant status which was significantly correlated with improved cognitive function and mood.
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How to cite this article

Yusr Mohamed Ibrahim Kazem, Maha Abdel-Moaty, Salwa Mostafa El Shebini, Nihad Hassan Ahmed, Suzanne Fouad and Salwa Tawfic Tapozada, 2017. Constipation, Oxidative Stress in Obese Patients and their Impact on Cognitive Functions and Mood, the Role of Diet Modification and Foeniculum vulgare Supplementation. Journal of Biological Sciences, 17: 312-319.

DOI: 10.3923/jbs.2017.312.319

URL: https://scialert.net/abstract/?doi=jbs.2017.312.319

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