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Journal of Biological Sciences
  Year: 2013 | Volume: 13 | Issue: 6 | Page No.: 499-506
DOI: 10.3923/jbs.2013.499.506
 
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An Attempt to Enhance Select Secondary Metabolite of Artemisia annua L.
Afaq Ahmad Malik, Sanghmitra Suryapani, Javed Ahmad, Shahid Umar, M.Z. Abdin and S.R. Mir

Abstract:
Artemisinin and its derivatives are potent anti-malarials and have become essential components of Artemisinin Based Combination Therapies (ACTs) for malarial treatment. Over 1 million deaths and 300-500 million cases of malaria are reported annually. Production of artemisinin is less as regards its world demand and access to ACTs is still limited in worst hit countries. Economics of artemisinin yield from A. annua crops determines the cost and availability of ACTs worldwide. Artemisinin yield from Artemisia annua depends on a number of factors including improved agricultural practices. An experiment was conducted in this regard to assess the impact of organic residues from urban areas and industries on A. annua L. Enhancement in artemisinin content, artemisinin yield, herb dry yield and plant characteristics were observed by the application of industrial wastes. Highest artemisinin content in leaf (0.53%) was found at flower initiation stage and highest artemisinin yield (29.97 kg ha-1) was obtained from sewage sludge biosolid treatment. The study reveals that organic waste amendments enhance herbage yield and artemisinin content so these, can be utilized for the commercial production of A. annua with additional benefits of mitigation of environmental pollution caused by the accretion of these large quantities.
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How to cite this article:

Afaq Ahmad Malik, Sanghmitra Suryapani, Javed Ahmad, Shahid Umar, M.Z. Abdin and S.R. Mir, 2013. An Attempt to Enhance Select Secondary Metabolite of Artemisia annua L.. Journal of Biological Sciences, 13: 499-506.

DOI: 10.3923/jbs.2013.499.506

URL: https://scialert.net/abstract/?doi=jbs.2013.499.506

 
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