Subscribe Now Subscribe Today
Science Alert
 
FOLLOW US:     Facebook     Twitter
Blue
   
Curve Top
Journal of Biological Sciences
  Year: 2013 | Volume: 13 | Issue: 3 | Page No.: 158-162
DOI: 10.3923/jbs.2013.158.162
Bioassay-guided Isolation of Antifungal Plumericin from Allamanda Species (Apocynaceae)
Farah F. Haron, Kamaruzaman Sijam, Dzolkhifli Omar and Mawardi Rahmani

Abstract:
Anthracnose is an economically important disease that can cause 10 to 80% yield reduction in the market with its typical symptoms of dark spots, sunken necrotic tissues and concentric rings of acervuli on fruits. One of the important methods to control the disease is by using antifungal agents derived from plant. Preliminary study indicated that the extracts of Allamanda species have the potential to be developed as the target agent. Five Allamanda species were extracted and screened for antifungal activity against plant pathogenic fungus Colletotrichum gloeosporioides by using poison agar technique. The three chloroform extracts of A. blanchetti, A. cathartica ‘Alba’ and A. cathartica ‘Jamaican Sunset’ exhibited potent inhibitory effects and suppressed the mycelial growth of C. gloeosporioides by up to about 70%. Further study by bioautography-guided fractionation of the extracts led to the isolation and identification of tetracyclic sesquiterpene plumericin as the antifungal agent. The structural determination of the compound was carried out by interpreting the IR, MS, 1D-NMR and 2D-NMR spectral data.
PDF Fulltext XML References Citation Report Citation
How to cite this article:

Farah F. Haron, Kamaruzaman Sijam, Dzolkhifli Omar and Mawardi Rahmani, 2013. Bioassay-guided Isolation of Antifungal Plumericin from Allamanda Species (Apocynaceae). Journal of Biological Sciences, 13: 158-162.

DOI: 10.3923/jbs.2013.158.162

URL: https://scialert.net/abstract/?doi=jbs.2013.158.162

 
COMMENT ON THIS PAPER
 
 
 

 

 
 
 
 
 
 
 
 
 

 
 
 
 
 
 
 
 
 
 

       

       

Curve Bottom