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Journal of Biological Sciences
  Year: 2011 | Volume: 11 | Issue: 5 | Page No.: 367-373
DOI: 10.3923/jbs.2011.367.373
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Status of Selected Hematological and Biochemical Parameters in Malaria and Malaria-typhoid Co-infection

O.T. Kayode, A.A.A. Kayode and O.O. Awonuga

There has been high incidence of malaria and typhoid co-infection in Nigeria lately but no documented study has really considered its impact on the biochemical status of the patients. The aim of this study was to investigate the effect of malaria and malaria-typhoid co-infection on some hematological and biochemical parameters in infected patients. A total of 66 febrile patients and 10 apparently healthy persons from Bells University of Technology and Covenant University Health Centers, Ota, Ogun State were screened for the presence of plasmodium falciparum and salmonella typhi. Levels of Neutrophils, Lymphocytes, White Blood Cells, Packed Cell Volume (PCV), Albumin, Urea, Glucose, Total Bilirubin, Total Protein and Creatinine were estimated in the blood plasma of the study groups. A significant increase (p<0.05) in Creatinine, Urea and Total Bilirubin levels, Neutrophils and White Blood Cell counts were observed in both the malaria and co-infected patients as compared to the control. However, Albumin, Glucose, PCV, Lymphocytes and Total Protein levels were significantly reduced (p<0.05) in both the malaria and co-infected patients. This study indicates alterations in these parameters and therefore recommends proper monitoring during treatment in order to reverse them to normal levels.
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  •    Liver Function Assessment in Malaria, Typhoid and Malaria-Typhoid Co-Infection in Aba, Abia State, Nigeria
  •    Assay of Glucose 6-phosphate Dehydrogenase Enzyme and its Correlation with Disease Prevalence in Patients with Plasmodium falciparum Malaria
  •    Evaluation of Antioxidant Levels and Trace Element Status in Nigerian Sickle Cell Disease Patients with Plasmodium Parasitaemia
  •    An Antisalmonellal Agent from the Leaves of Glossocalyx brevipes Benth (Monimiaceae)
  •    Changes in Serum Glucose and Triacylglycerol Levels Induced by the Co-administration of Two Different Types of Antimalarial Drugs among Some Plasmodium falciparum Malarial Patients in Edo-delta Region of Nigeria
  •    The Association of K76T Mutation in Pfcrt Gene and Chloroquine Treatment Failure in Uncomplicated Plasmodium falciparum Malaria in a Cohort of Nigerian Children
How to cite this article:

O.T. Kayode, A.A.A. Kayode and O.O. Awonuga, 2011. Status of Selected Hematological and Biochemical Parameters in Malaria and Malaria-typhoid Co-infection. Journal of Biological Sciences, 11: 367-373.

DOI: 10.3923/jbs.2011.367.373






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