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Journal of Biological Sciences

Year: 2010 | Volume: 10 | Issue: 7 | Page No.: 682-685
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Authors

P. Thirunavukkarasu

T. Ramanathan

N. Ravichandran

L. Ramkumar

Keywords

The objective of this study was to determine the potential anti-microbial activity of aqueous ethanolic and chloroform extracts from 3 medicinal plants against bacteria and some fungal strains. The antimicrobial efficacy of Citrullus colocynthis, Citrullus lanatus and Citrullus vulgaris, was evaluated against Gram negative, positive and some fungal strains and including Esherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Bacillus subtilis and Bacillus pumilus some fungal Candida albicans, Aspergillus niger, Penicillium chrysogenum and Penicillium chrysogenum using agar well diffusion method at concentration levels (100 mg mL-1). Among the tested plants, Citrullus colonthis extract showed the highest antibacterial and anti fungal activity and all bacterial and fungal strains at 100 mg mL-1. In addition, almost all species of plants were found to have activity on at least two microbial strains. However, the diameters of inhibition zone were different according to the kinds and concentrations of plant extracts and bacterial and fungal strains. The ethanol extract of citrullus colocynthis was very active against bacterial and fungal at a concentration of 100 mg mL-1. But Trichosporon begelli showed that no zone inhibition in C. valgaries plants of ethanol and chloroform extracts.
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