Subscribe Now Subscribe Today
Science Alert
 
Blue
   
Curve Top
Journal of Biological Sciences
  Year: 2010 | Volume: 10 | Issue: 1 | Page No.: 53-57
DOI: 10.3923/jbs.2010.53.57
 
Facebook Twitter Digg Reddit Linkedin StumbleUpon E-mail

Bone Marrow Stromal Cells for the Treatment of Spinal Cord Injury in Rats

M. Tehranipour

Abstract:
There are extensive evidences that degeneration process after spinal cord injury could be a good reason for nervous system (peripheral and/or central) problems. In this study the effects of cell administration on Alpha motoneurons regeneration after Spinal Cord Injury (SCI) in rat was investigated. Twenty four male Wistar rats divided to 3 groups (control, Spinal Cord Injury (SCI), (SCI) + stem cell administration n = 8). After 4 weeks the lumber segments of spinal cord were sample, processed, sectioned serially and stained with toluidine blue (pH = 4.65). By using sterological quantitative technique (physical dissector), the number of alpha motoneurons in the right ventral horns of spinal cord were counted and compared with each other. Statistical analysis showed treatment with stem cell at four week significantly (p<0.05) reduced neuronal damage and progress the regeneration. The numerical density in this group is near to control group. Then it is consulted that cell administration could reduce the degeneration rate of Alpha motoneurons after Spinal Cord Injury (SCI) in rat.
PDF Fulltext XML References Citation Report Citation
 RELATED ARTICLES:
  •    Effect of Donor Cells Concentration on Colonization of Human Spermatogonial Stem Cells in Recipient Mouse Testes
  •    Stem Cells Research and its Applications: A Review
How to cite this article:

M. Tehranipour , 2010. Bone Marrow Stromal Cells for the Treatment of Spinal Cord Injury in Rats. Journal of Biological Sciences, 10: 53-57.

DOI: 10.3923/jbs.2010.53.57

URL: https://scialert.net/abstract/?doi=jbs.2010.53.57

COMMENT ON THIS PAPER
 
 
 

 

 
 
 
 
 
 
 
 
 

 
 
 
 
 
 
 
 
 
 

Curve Bottom