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Journal of Biological Sciences
  Year: 2009 | Volume: 9 | Issue: 3 | Page No.: 288-291
DOI: 10.3923/jbs.2009.288.291
Prevalence of Haemoglobin Variants in Malaria Endemic Northeast India
S.K. Sharma and J. Mahanta

Abstract:
The present study is an attempt to evaluate the relationship of haemoglobinopathies, particularly Hb E and Plasmodium falciparum malaria in northeastern region of India. The diverse autochthonous inhabitant of this part of India exhibits variable gene frequency for βE-globin gene. The geo-climatic condition of the region supports transmission of Plasmodium falciparum malaria in northeastern parts of India. The study revealed that HbE is predominant with a variable gene frequencies in ethnic groups affiliated to Tibeto-Burman linguistic families. Prevalence of Hb E is also associated with the linguistic affiliation of various Tibeto-Burman linguistic families inhabiting in malaria endemic northeast India. We have also observed a positive correlation (R2 = 0.703) of βE-globin gene frequency and mean incidence of Plasmodium falciparum infection (Pf %) in malaria endemic zones.
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How to cite this article:

S.K. Sharma and J. Mahanta, 2009. Prevalence of Haemoglobin Variants in Malaria Endemic Northeast India. Journal of Biological Sciences, 9: 288-291.

DOI: 10.3923/jbs.2009.288.291

URL: https://scialert.net/abstract/?doi=jbs.2009.288.291

 
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