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Journal of Biological Sciences
  Year: 2009 | Volume: 9 | Issue: 3 | Page No.: 249-253
DOI: 10.3923/jbs.2009.249.253
Study of Prevalence and Antimicrobial Susceptibility Pattern of Bacteria Isolated from Blood Cultures
M. Mehdinejad, A.D. Khosravi and A. Morvaridi

The aim of present study was to investigate the type of bacteria isolated from blood cultures and determination of their antibiotic susceptibility pattern. During 18 months, 2790 blood culture samples were screened. The positive blood cultures were examined and the organisms were identified as per standard procedures. Antimicrobial susceptibility testing was performed for all isolates by use of disk diffusion technique, according to CLSI guidelines. From total blood culture samples, 155 (5.6%) were positive. The most common isolated gram negative bacilli were Klebsiella pneumoniae 52 (33.5%), Eschericia coli 32 (20.6%) and Enterobacter sp. 15 (9.7%) and coagulase negative staphylococci (CONS) as predominant gram positive cocci, all the isolated bacteria showed the highest degree of resistance to ampicillin (98.7%), cefalexin (70.3%) and trimethoprim- sulfamethoxazole (69.7%). Gram positive cocci were also fully resistant to penicillin. In conclusion, present study revealed that both gram positive and gram negative bacteria were responsible for bloodstream infections and most of the strains were multi-drug resistant. The most common isolated bacteria from blood cultures were Klebsiella pneumoniae and E. coli. Ciproflexacine was the most effective antibiotic against gram negative bacilli, while vancomysin was mostly effective against gram positive cocci.
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How to cite this article:

M. Mehdinejad, A.D. Khosravi and A. Morvaridi, 2009. Study of Prevalence and Antimicrobial Susceptibility Pattern of Bacteria Isolated from Blood Cultures. Journal of Biological Sciences, 9: 249-253.

DOI: 10.3923/jbs.2009.249.253








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