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Journal of Biological Sciences
  Year: 2008 | Volume: 8 | Issue: 4 | Page No.: 767-772
DOI: 10.3923/jbs.2008.767.772
Effect of Oral Aluminum Chloride Administration During Lactation on Short and Long-Term Memory of Their Offspring
Moazedi Ahmad Ali, Ehsani Vostacolaee Simin and Chinipardaz Rahim

Abstract:
To study the relationship between aluminum chloride (AlCl3) and memory of their offspring male. Five groups of adult Wistar rats (200 ± 30) were taken for this experiment. Female rats were concurrently exposed (0, 200, 400, 600 and 800 mg/kg/day) of aluminum administered as AlCl3 in drinking water for two weeks. Forty-five after birth, a shuttle box was used to test memory. This experiment showed that maternal dietary exposure Alcl3 (200, 400 and 600 mg/kg/day) doses after two weeks during lactation, there were no different on the working memory of their offspring for any of groups. But rat which received AlCl3 800 mg/kg/day during lactation, has shown significant impairment in working memory of their offspring (p < 0.001) (p < 0.05). This study has demonstrated that (200, 400 and 600 mg/kg/day) AlCl3 consumption for two weeks during lactation had no effect. But consumption of AlCl3 800 mg/kg/day during lactation, can impairment in (short-term and long-term) memory of their offspring.
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How to cite this article:

Moazedi Ahmad Ali, Ehsani Vostacolaee Simin and Chinipardaz Rahim, 2008. Effect of Oral Aluminum Chloride Administration During Lactation on Short and Long-Term Memory of Their Offspring. Journal of Biological Sciences, 8: 767-772.

DOI: 10.3923/jbs.2008.767.772

URL: https://scialert.net/abstract/?doi=jbs.2008.767.772

 
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