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Journal of Biological Sciences

Year: 2008 | Volume: 8 | Issue: 6 | Page No.: 1062-1066
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Authors

A.O.T. Ashafa

D.S. Grierson

A.J. Afolayan

Keywords

Research Article

Antimicrobial Activity of Extracts from Felicia muricata Thunb

A.O.T. Ashafa, D.S. Grierson and A.J. Afolayan
The antimicrobial activities of the acetone, methanol and water extracts from the leaves, stems and roots of this herb were investigated against 10 bacterial and 5 fungal species using the dilution method on solid agar medium. The acetone extracts from the leaf and root were active against Gram-positive bacteria with Minimum Inhibitory Concentration (MIC) ranging between 1.0 and 7.0 mg mL-1, whereas the acetone stem extract was able to inhibit all the bacterial strains at 0.5-7.0 mg mL-1. The methanol extracts of the 3 plant parts showed activity against all the bacterial isolates with MIC values ranging between 0.1 and 10.0 mg mL-1. Again all the extracts exhibited appreciable activity against all the fungi species investigated. The methanol extract of the root showed 100% inhibition against Aspergillus niger, A. flavus and Penicilium notatum at 5 mg mL-1 while it was 88.61% inhibition in Mucor hiemalis. The ability of the extracts of F. muricata to inhibit the growth of several bacteria and fungi is an indication of its broad-spectrum antimicrobial potential which may be employed in the management of bacterial and fungal infections.
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