Additional Possibility of Data Analysis of Enzyme Inhibition and Activation. 8. A Choice of the Equations for Calculation of the Initial Reaction Rates vi and va in Enzyme Inhibition and Activation


	Journal of Biological Sciences
	Year: 2007 \| Volume: 7 \| Issue: 3 \| Page No.: 506-513 DOI: 10.3923/jbs.2007.506.513

Additional Possibility of Data Analysis of Enzyme Inhibition and Activation. 8. A Choice of the Equations for Calculation of the Initial Reaction Rates v_i and v_a in Enzyme Inhibition and Activation

V.I. Krupyanko

Abstract: The equations for calculation of initial rates of the associative, Iv_i type and catalytic, III_i type, of enzyme inhibition are most frequently used in practice of calculation the initial rates of inhibited (v_i) enzymatic reactions (Appendix B1, Eq. B4 and B3). In some cases these equations are used with arbitrary modifications that may lead to incorrect calculation of respective parameters of reactions. Now the equations for calculation of initial rates (v_i) and (v_a) have been deduced for all seven types of inhibited (I_i, I_ii, III_i, IV_i, V_i, VI_i, VII_i) and seven types of activated (I_a, II_a, III_a, IV_a, V_a, VI_a, VII_a) enzymatic reactions and it need to discuss the rule of choice (and conditions of applicability) of equation for processing experimental data of each these types of enzymatic reactions. Examples of choice the equations for calculation of the initial reaction rates v_i and v_a (and k_i, k_a) constants are given.

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How to cite this article:

V.I. Krupyanko , 2007. Additional Possibility of Data Analysis of Enzyme Inhibition and Activation. 8. A Choice of the Equations for Calculation of the Initial Reaction Rates v_i and v_a in Enzyme Inhibition and Activation . Journal of Biological Sciences, 7: 506-513.

DOI: 10.3923/jbs.2007.506.513

URL: https://scialert.net/abstract/?doi=jbs.2007.506.513

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