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Journal of Biological Sciences
  Year: 2006 | Volume: 6 | Issue: 2 | Page No.: 393-397
DOI: 10.3923/jbs.2006.393.397
 
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Correlation of Serum Magnesium with Serum Parathormone in Regular Hemodialysis Patients
Hamid Nasri, Shahin Shirani M.D. and Azar Baradaran

Abstract:
To consider the relationship of serum magnesium with the activity of the parathyroid gland in maintenance hemodialysis patients we designed a study to investigate the role of serum magnesium in regulating the parathyroid secretion. The study was conducted on patients undergoing maintenance hemodialysis treatment. Predialysis serum calcium, phosphorus, magnesium, alkaline phosphatase, intact serum PTH (iPTH), serum 25-hydroxy vitamin D (25-OH Vit D) and plasma HCO3 were measured. The Urea Reduction Rate, duration and dosage of hemodialysis treatment were calculated also. In this study no significant correlation of serum magnesium with duration of hemodialysis treatment, alkaline phosphatase, plasma HCO3, serum calcium and phosphorus patients were seen. In all patients a near significant inverse correlation of serum magnesium with iPTH (r = -0.30 , p = 0.079 ) was found, also a significant positive correlation of serum magnesium with serum 25-hydroxy vitamin D levels ( r = 0.40, p = 0.009 ) was seen. Earlier research concluded that some factors other than serum magnesium may be more important in the regulation of parahormone secretion in hemodialysis patients. A positive and strong association between serum magnesium with 25-hydroxy vitamin D level, needs to more attention to this aspect of hemodialysis patients.
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How to cite this article:

Hamid Nasri, Shahin Shirani M.D. and Azar Baradaran, 2006. Correlation of Serum Magnesium with Serum Parathormone in Regular Hemodialysis Patients. Journal of Biological Sciences, 6: 393-397.

DOI: 10.3923/jbs.2006.393.397

URL: https://scialert.net/abstract/?doi=jbs.2006.393.397

 
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