Additional Possibility of Data Analysis of Enzyme Inhibition and Activation.1: Equations for Calculation of the Ka and Ki Constants of Enzyme Activation and Nontrivial Types of Enzyme Inhibition


	Journal of Biological Sciences
	Year: 2005 \| Volume: 5 \| Issue: 1 \| Page No.: 82-91 DOI: 10.3923/jbs.2005.82.91

Additional Possibility of Data Analysis of Enzyme Inhibition and Activation.1: Equations for Calculation of the K_a and K_i Constants of Enzyme Activation and Nontrivial Types of Enzyme Inhibition

Vladimir I. Krupyanko

Abstract: By taking into consideration symmetry of the position of L_i vectors of enzymatic inhibited reactions to L_a vectors of activated enzymatic reactions in the three-dimensional K`_mV`I coordinate system and symmetric antidirectivity of tendencies in the course of change of K`_m and V` parameters of inhibited and activated enzymatic reactions similar by the type, a parametric classification of the types of enzymatic reactions was proposed, the equations for calculation of K_a constants of enzyme activation and K_i constants of nontrivial types of enzyme inhibition were obtained and some corrections introduced into practice of using the coordinates of intercepts and slopes for calculation of these constants. Examples of calculation of K_a and K_i constants are given.

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How to cite this article:

Vladimir I. Krupyanko , 2005. Additional Possibility of Data Analysis of Enzyme Inhibition and Activation.1: Equations for Calculation of the K_a and K_i Constants of Enzyme Activation and Nontrivial Types of Enzyme Inhibition. Journal of Biological Sciences, 5: 82-91.

DOI: 10.3923/jbs.2005.82.91

URL: https://scialert.net/abstract/?doi=jbs.2005.82.91

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