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Journal of Applied Sciences

Year: 2012 | Volume: 12 | Issue: 18 | Page No.: 1932-1938
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Authors

J. Jeba Emilyn

K. Ramar

Keywords

Research Article

An Intelligent Mining Framework based on Rough Sets for Clustering Gene Expression Data

J. Jeba Emilyn and K. Ramar
The main aim of this study is not only to develop a biclustering algorithm that would successfully identify gene patterns but also to propose an intelligent clustering framework that would improve the cluster quality. Our framework for mining co-regulated genes from gene expression dataset is composed of three important steps: a preprocessing step to refine the data, an intelligent procedure to predict the possible number of biclusters and a procedure based on rough sets to cluster the gene datasets. Our algorithm is said to be intelligent, in the sense that it can predict the possible number of biclusters. Since, the algorithm is based on rough sets, there are high possibilities of placing a gene in more than one bicluster and thus allows overlapping of biclusters. A theoretical understanding of the proposed algorithm is analyzed and results are illustrated with different gene expression data sets. The analysis and the experiment shows that the method is more intelligent and efficient.
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