Subscribe Now Subscribe Today
Science Alert
 
Blue
   
Curve Top
Journal of Applied Sciences
  Year: 2009 | Volume: 9 | Issue: 24 | Page No.: 4232-4239
DOI: 10.3923/jas.2009.4232.4239
 
Facebook Twitter Digg Reddit Linkedin StumbleUpon E-mail

Performance Evaluation through CFD Simulation and Field Measurement on a Bio-Cleanroom for Vaccine Storage

Fu-Jen Wang, Yat-Huang Yau, Zhuan-Ru Liu and Yin-Rui Zheng

Abstract:
Modern biomedical industries are increasingly turning to cleanroom technology for the environmental control or the development of new products. It is vital to provide thermo-stabilized environment and cost-effective operation conditions for bio-tech industries as well as for influenza vaccine plants. In this study, field measurement and numerical simulation of a full-scale bio-cleanroom has been carried out at a vaccine plant in Taiwan. Computational Fluid Dynamics (CFD) simulation were also conducted to investigate the temperature and airflow distribution as well as the energy saving potential of the bio-cleanroom. Validation of bio-cleanroom for egg-grown vaccine production was performed to meet the specification set at design stage. The results from computer simulation revealed that the improvement of energy consumption could be achieved satisfactorily by reduction of supply airflow rate and increase of supply air temperature. Different velocity and temperature of supply air could be assessed extensively not only by airflow and temperature distribution but also by transient simulation to achieve the design specification of 4°C for vaccine storage. It was also expected that CFD aided simulation could identify strategies for best practice at design stage as well as reduce running cost at full operation.
PDF Fulltext XML References Citation Report Citation
 RELATED ARTICLES:
  •    Thermal Comfort Assessment of Underfloor vs. Overhead Air Distribution System
How to cite this article:

Fu-Jen Wang, Yat-Huang Yau, Zhuan-Ru Liu and Yin-Rui Zheng, 2009. Performance Evaluation through CFD Simulation and Field Measurement on a Bio-Cleanroom for Vaccine Storage. Journal of Applied Sciences, 9: 4232-4239.

DOI: 10.3923/jas.2009.4232.4239

URL: https://scialert.net/abstract/?doi=jas.2009.4232.4239

COMMENT ON THIS PAPER
 
 
 

 

 
 
 
 
 
 
 
 
 

 
 
 
 
 
 
 

Curve Bottom