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Journal of Applied Sciences

Year: 2008 | Volume: 8 | Issue: 5 | Page No.: 881-885
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Authors

Sooad Al- Daihan

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Research Article

Measurement of Selected Enzymatic Activities in Solanum nigrum-Treated Biomphalaria arabica Snails

Sooad Al- Daihan
In the present study, glucose, acid and alkaline phosphatases (ACP and ALP), α-amylase and lipase were measured for the first time in tissue homogenates of Biomphalaria arabica snails, molluscan intermediate host for Schistosoma mansoni in Saudi Arabia. Also, the effect of sublethal concentrations (LC25) of dry powdered Solanum nigrum leaf was tested as plant molluscicide against this snail species. The tested enzymes were altered in molluscicide-treated snails compared to control. While ALP and amylase were slightly affected, ACP and lipase were significantly altered. Glucose as an important energy source for a successful schistosome-snail relationship was significantly reduced in molluscicide-treated snails. In conclusion, sublethal concentration of the molluscicide showed potent effect in disturbing snail biochemistry which may render them physiologically unsuitable for the developing of schistosome parasite. This could be considered as a promising strategy to control the disease.
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Prof.Dr. Ahmed Tarek Sharaf El-Din Reply

This paper is a master piece of science. But it needs some explanation in the discussion especially how these plant extract affect enzymes of snails (mode of action).

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