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Journal of Applied Sciences
  Year: 2008 | Volume: 8 | Issue: 21 | Page No.: 3999-4003
DOI: 10.3923/jas.2008.3999.4003
Identification of Burkholderia pseudomallei Mimotope using Phage Display Approach
Kek Heng Chua, Hwa Chia Chai and S.D. Puthucheary

Abstract:
This study reportsa sequential biopanning against serum obtained from a patient infected with B. pseudomallei using a phage display peptide library. A peptide bearing the consensus sequence NKNSFDAWLQSF was obtained after 3 rounds of biopanning and it partly resembles the sequence 35FDAWLAAQEF44 of B. pseudomallei site-specific recombinase, which is a phage integrase family protein. Overall, the mimotope obtained in this study could be a potential candidate for the development of a cost effective diagnostic test or vaccine in the future.
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How to cite this article:

Kek Heng Chua, Hwa Chia Chai and S.D. Puthucheary, 2008. Identification of Burkholderia pseudomallei Mimotope using Phage Display Approach. Journal of Applied Sciences, 8: 3999-4003.

DOI: 10.3923/jas.2008.3999.4003

URL: https://scialert.net/abstract/?doi=jas.2008.3999.4003

 
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