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Journal of Applied Sciences
  Year: 2006 | Volume: 6 | Issue: 14 | Page No.: 2959-2962
DOI: 10.3923/jas.2006.2959.2962
Toxicity of Sumithion in Albino Rats: Hematological and Biochemical Studies
Zuhair Y. Al. Sahhaf

Abstract:
This study was carried out to investigate the hematological and biochemical effects of the organophosphate insecticide, sumithion, in albino rats. Animals were treated with sumathion at a dose level of 60 mg kg-1 body weight (1/4 LD50 ) daily for 12 days. It was found that erythrocytes (RBCs) count, haemoglobin contents, Mean Corpuscle Volume (MCV) and Mean Corpuscle Haemoglobin Concentration (MCHC) were almost similar in control and treated animals. On the other hand, the results showed that the haemotocrite value, number of leucocytes (WBCs) as well as the lymphocytes percentage were significantly increased in treated animals The platelets were significantly decreased. The results also showed that serum total protein was decreased while triglycerides showed insignificant increase in comparison with control. Cholesterol and creatinine significantly increased after 12 days of treatment. Histological examination of kidney of treated rats revealed impairment of the renal tissues.
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How to cite this article:

Zuhair Y. Al. Sahhaf , 2006. Toxicity of Sumithion in Albino Rats: Hematological and Biochemical Studies. Journal of Applied Sciences, 6: 2959-2962.

DOI: 10.3923/jas.2006.2959.2962

URL: https://scialert.net/abstract/?doi=jas.2006.2959.2962

 
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