Science Alert
Curve Top
Journal of Applied Sciences
  Year: 2005 | Volume: 5 | Issue: 2 | Page No.: 327-333
DOI: 10.3923/jas.2005.327.333
Facebook Twitter Digg Reddit Linkedin StumbleUpon E-mail

Studies of Antimicrobial Activity of two Synthetic 2`, 4`, 6`-trioxygenated Flavones

Sayed Alam and Sohel Mostahar

Two 2`, 4`, 6`-trioxygenated flavones has been synthesized and tested for antibacterial and antifungal activities along with their corresponding chalcones against four human pathogenic bacteria and five plant as well as molds fungi. UV, IR and 1H NMMR techniques together with elemental analysis elucidated the structures of the synthesized compounds. The antibacterial and antifungal screen was performed in vitro by the filter paper disc diffusion method and poisoned food technique. Compound 6 and 7 showed antibacterial activity but their corresponding chalcones didn`t show any activity against tested bacteria. Compound 4 and its corresponding chalcone 6 didn`t show any antifungal activity where as compound 5 and its flavone 7 showed moderate antifungal activity against Penicillium sp and Colletorichum gloeosporioides.
PDF Fulltext XML References Citation Report Citation
  •    Chemical Constituents and Cytotoxic Activity of Polyalthia cauliflora var. cauliflora
  •    Damage in Fungal Morphology Underlies the Antifungal Effect of Lyophilisate of Granular Gland Secretion from Duttaphrynus melanostictus Frog
  •    Structure of Duttaphrynus melanostictus Frog Skin and Antifungal Potency of the Skin Extract
How to cite this article:

Sayed Alam and Sohel Mostahar, 2005. Studies of Antimicrobial Activity of two Synthetic 2`, 4`, 6`-trioxygenated Flavones. Journal of Applied Sciences, 5: 327-333.

DOI: 10.3923/jas.2005.327.333






Curve Bottom