Abstract: Genetic Algorithm (GA) has been successfully applied to codebook design for Vector Quantization (VQ). This work uses the facilities of the genetic algorithm (Crossover and Mutation Operations) to enhance the use of one popular compression method, Vector Quantization (VQ) method. After studying the VQ method, a new algorithm for mixing it with a Genetic Algorithm (GA) is proposed and implemented for testing on some popular image datasets. A good enhancement was recorded for the performance of the (VQ) method when mixed with the (GA). Some fidelity measures are calculated to evaluate the performance of the new proposed algorithm.