Enhancing Effect of Ginseng Stem-leaf Saponins on the Immune Responses in Vaccinated Calves with FMD Bivalent Vaccine


	International Journal of Virology
	Year: 2011 \| Volume: 7 \| Issue: 4 \| Page No.: 167-175 DOI: 10.3923/ijv.2011.167.175

Enhancing Effect of Ginseng Stem-leaf Saponins on the Immune Responses in Vaccinated Calves with FMD Bivalent Vaccine

Sonia A. Rizk, Eman M. El-garf and Abeer A. Talaat

Abstract: A comprehensive sero-immunological studies were conduced to reveal the adjuvant's effect of Ginseng Stem-leaf Saponins (GSLS) on the immune response of gel adjuvanted Bivalent Foot and Mouth Disease (FMD) vaccinated calves. These study conducted in two calve groups; group (A) vaccinated subcutaneously with bivalent Alhydragel adjuvanted (30)% FMD vaccine, while group (B) vaccinated subcutaneously with bivalent FMD vaccine adjuvanted with both Alhydragel and GSLS (10 mg/dose). The humeral and cellular immunoresponses were monitored in different tested groups that received the gel adjuvanted vaccine and the Alhydragel-GSLS adjuvanted vaccine. Results indicated that the higher immune responses were found in calves vaccinated with Alhydragel-GSLS adjuvanted vaccine up to 24 week while with Alhydragel alone was only up to 18 week.

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How to cite this article:

Sonia A. Rizk, Eman M. El-garf and Abeer A. Talaat, 2011. Enhancing Effect of Ginseng Stem-leaf Saponins on the Immune Responses in Vaccinated Calves with FMD Bivalent Vaccine. International Journal of Virology, 7: 167-175.

DOI: 10.3923/ijv.2011.167.175

URL: https://scialert.net/abstract/?doi=ijv.2011.167.175

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