Studies were conducted at the University of Benin, Benin City, Nigeria to examine the influence of combining rubber effluent with rock phosphate on some soil chemical properties as well as some agronomic characters of maize. The analysis of rubber effluent showed that it contains N, P, K, Ca Mg, Fe Mn, Zn and slightly acidic. It was also observed that the effluent had a pungent odour and colourless. In the first cropping, soil pH, N, Ca, Mg, K Na, Na, Fe, Mn, ECEC and Exchangeable acidity increased while the P and % carbon were reduced compared with control. In the second cropping, all the nutrient elements were reduced further. In the nutrient content of Maize, N, P increased up to 200,000l/(30 kg ha-1) while Ca, Na, Mg, K increased up to 200000l (60 kg ha-1). The trace elements content were not consistent. Similar trends were also recorded in the second cropping but the nutrient contents were reduced further. The N, P, K, Ca, Na, Al, Fe, Zn and Mn uptake were higher at 150,000l (30 kg ha-1) while the Mg uptake was higher at 250,000l (120 kg ha-1) At final harvest, 150,000l (30 kg ha-1) was significantly (p<0.05) better than other treatments including control in plant height, collar girth and leaf area. The number of leaves was not significantly different from one another in all the treatments. In the residual effect, all the agronomic characters measured were almost closing up with the first cropping.