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International Journal of Pharmacology
  Year: 2019 | Volume: 15 | Issue: 1 | Page No.: 1-9
DOI: 10.3923/ijp.2019.1.9
 
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Pharmacological Uses of Ginkgo biloba Extracts for Cardiovascular Disease and Coronary Heart Diseases

Zhiming Shu, Akhtar Hussain Shar, Mohamed Shahen , He Wang, Mahmoud Alagawany , Mohamed E. Abd El-Hack, Shahmir Ali Kalhoro, Muhammad Rashid and Piar Ali Shar

Abstract:
Globally the cardiovascular disease (CVDs) and coronary heart disease (CHD) are main cause of death. Ginkgo biloba is one of the oldest plants in the world, originating in China, science is known as the "living fossil". Ginkgo biloba leaves extract (GBLE) is a bioactive substance extracted from the Ginkgo biloba, the main active ingredients of Ginkgo flavonoids and ginkgolide compound, three or four, one of the most important Ginkgo biloba leaves extract is widely used as a drug or food additive in more than 130 countries. Thousands of years ago Asian and other region was use the traditional Chinese medicine (TCM), they verified some effective disorders. The medicinal uses of Ginkgo biloba have been widely used for various disease including cardiovascular disease and coronary heart disease. The properties of Ginkgo are mentioned here for example; improved blood flow, antioxidant, strengthens blood vessels, anti-inflammatory, relaxes the lungs, vasodilator and circulatory system tonic. Ginkgo biloba leaves extract also appears to have an anti-inflammatory impact that may make it useful in the future for situations like organ transplants and multiple sclerosis. However, due to the multi component of the herb, up to now the molecular mechanisms of action and signaling pathways leading to the therapeutic effects of GBLE remain, still, poorly understood.
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How to cite this article:

Zhiming Shu, Akhtar Hussain Shar, Mohamed Shahen, He Wang, Mahmoud Alagawany, Mohamed E. Abd El-Hack, Shahmir Ali Kalhoro, Muhammad Rashid and Piar Ali Shar, 2019. Pharmacological Uses of Ginkgo biloba Extracts for Cardiovascular Disease and Coronary Heart Diseases. International Journal of Pharmacology, 15: 1-9.

DOI: 10.3923/ijp.2019.1.9

URL: https://scialert.net/abstract/?doi=ijp.2019.1.9

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