Science Alert
 
Blue
   
Curve Top
International Journal of Pharmacology
  Year: 2018 | Volume: 14 | Issue: 8 | Page No.: 1060-1065
DOI: 10.3923/ijp.2018.1060.1065
 
Facebook Twitter Digg Reddit Linkedin StumbleUpon E-mail

Spectral Properties of the Interaction Between Hesperidin of Tangerine Peel’s Active Ingredient with Protein
Tianhu Wang , Yuxia Sun, Tianyu Chen and Yue Hu

Abstract: Background and Objective: Tangerine peel has high medical value due to its physiological active including volatile components, flavonoids, alkaloids etc. In this paper, the aim of this work was to study the spectral properties of tangerine peel and the binding interaction between hesperidin of its effective components and bovine serum albumin (BSA). Methodology: The fluorescence spectroscopy was used with the different excitation wavelength under simulative physiological conditions. The dynamic quenching mechanism could be described by the Stern-Volmer equation. The binding parameters between hesperidin and BSA was calculated by double logarithmic equation. Results: The results show the fluorescence peak of tangerine peel is about 448 nm and there a certain red shift occur with the increase of the excitation. The investigation of between BSA and hesperidin show that hesperidin could intact with BSA and the hesperidin-BSA complex was formed. The binding constants between hesperidin and BSA are 3.26, 2.71 and 1.98×104 mol–1 L at 298, 305 and 310 K, respectively, indicating the binding capacity of hesperidin to BSA was weakened with the increasing temperature. Conclusion: It is concluded that, the peak wavelength of tangerine peel is about 448 nm, the hesperidin could interact with BSA, the fluorescence quenching of BSA caused by hesperidin is a static quenching.
PDF Fulltext XML References Citation Report Citation
How to cite this article:

Tianhu Wang, Yuxia Sun, Tianyu Chen and Yue Hu, 2018. Spectral Properties of the Interaction Between Hesperidin of Tangerine Peel’s Active Ingredient with Protein. International Journal of Pharmacology, 14: 1060-1065.

DOI: 10.3923/ijp.2018.1060.1065

URL: https://scialert.net/abstract/?doi=ijp.2018.1060.1065
COMMENT ON THIS PAPER
 
 
 

 
  Bullet Navigation
 
  Page Icon Online First
  Page Icon Current Issue
  Page Icon Previous Issues
  Page Icon Editorial Board
  Page Icon Submit a Manuscript
  Page Icon Guide to Authors
  Page Icon Subscribe to E-alerts

  Bullet Indexed In
 
  Page Icon ASCI-Database
  Page Icon Asian Digital Library
  Page Icon Chemical Abstract Services
  Page Icon EMBASE
  Page Icon Google Scholar
  Page Icon ISI Web of Knowledge
  Page Icon Science Citation Index (EXP)
  Page Icon SCIMAGO
  Page Icon Thomson ISI



Science Alert
Curve Bottom