Charge-transfer Complexes Formed between the Sweeteners Saccharin Drug and Acido Acceptors: Structural, Thermal and Morphological Features

Research Article

Charge-transfer Complexes Formed between the Sweeteners Saccharin Drug and Acido Acceptors: Structural, Thermal and Morphological Features

Ahmed M. Naglah, Mohamed A. Al- Omar, Abdel Majid A. Adam and Moamen S. Refat

Saccharin (sacH) is a sugar substitute sweetening agent used extensively in dietary products. It is about 300 times sweeter than sucrose. This study highlighted the structural chemistry of Charge Transfer (CT) complexes formed from the interactions of two acido acceptors (CLA and PA) with sacH. The IR and ¹H NMR revealed evidence of significant intermolecular interactions between N-H group in the sacH and O-H group in the acido acceptors based on their characteristic shifts. The TG and DTA experiments were carried out to investigate the thermal properties of the obtained complexes. Their morphological features were also investigated using Optical Light Microscope (OLM). The OLM micrograph patterns indicate the formation of high quality colored crystals. This study provided the essential basics for understanding the complexation chemistry of saccharin.

PDF Fulltext XML References Citation

How to cite this article

Ahmed M. Naglah, Mohamed A. Al- Omar, Abdel Majid A. Adam and Moamen S. Refat, 2015. Charge-transfer Complexes Formed between the Sweeteners Saccharin Drug and Acido Acceptors: Structural, Thermal and Morphological Features. International Journal of Pharmacology, 11: 929-937.

DOI: 10.3923/ijp.2015.929.937

URL: https://scialert.net/abstract/?doi=ijp.2015.929.937

International Journal of Pharmacology

Article Trend

Total views 64

Authors

Ahmed M. Naglah

Mohamed A. Al- Omar

Abdel Majid A. Adam

Moamen S. Refat

Keywords

Research Article

Charge-transfer Complexes Formed between the Sweeteners Saccharin Drug and Acido Acceptors: Structural, Thermal and Morphological Features

How to cite this article

Leave a Comment