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International Journal of Pharmacology
  Year: 2014 | Volume: 10 | Issue: 8 | Page No.: 524-527
DOI: 10.3923/ijp.2014.524.527
Protective Effects of Ginsenosides Rb2 on Irradiation-Induced Hematopoietic System Injury in the Mice
Qike Zhang, Baixia Yang, Xiaogang Zhai, Kuiling Zhao, Zhijun Wu, Qiwei Zhu, Jinlin Zhang, Xiaofang Wei, Yingling Zhao, Jing Cai and Zili Zhu

Abstract:
Ginsenosides Rb2 is an extract of ginseng which has a broad range of therapeutic and pharmacological applications. This study, aimed to explore the protective effects of Rb2 on irradiation-induced hematopoietic system injury in mice. The Rb2 was administrated twice a day to the mice for 3 days and mice were irradiated for 10 Gy after the last injection. The weight and the activity of the mice were evaluated daily. On day 14 after irradiation, blood cell counts were analyzed. It was found that Rb2 alleviated radiation-induced changes in blood cell counts. Compared with irradiation alone group, mice in Rb2 group showed better behaviors. Ginsenosides Rb2 may be a beneficial agent against radiation-induced blood system damage.
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How to cite this article:

Qike Zhang, Baixia Yang, Xiaogang Zhai, Kuiling Zhao, Zhijun Wu, Qiwei Zhu, Jinlin Zhang, Xiaofang Wei, Yingling Zhao, Jing Cai and Zili Zhu, 2014. Protective Effects of Ginsenosides Rb2 on Irradiation-Induced Hematopoietic System Injury in the Mice. International Journal of Pharmacology, 10: 524-527.

DOI: 10.3923/ijp.2014.524.527

URL: https://scialert.net/abstract/?doi=ijp.2014.524.527

 
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