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International Journal of Pharmacology

Year: 2013 | Volume: 9 | Issue: 7 | Page No.: 442-453
DOI: 10.3923/ijp.2013.442.453

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Authors


Farooq Anwar

Country: Pakistan

Nusrat Shaheen

Country: Pakistan

Ghulam Shabir

Country: Pakistan

Muhammad Ashraf

Country: Pakistan

Khalid M. Alkharfy

Country: Pakistan

Anwarul-Hassan Gilani


Keywords


  • Lantana camara
  • olvent extracts
  • olvent extracts
Research Article

Variation in Antioxidant Activity and Phenolic and Flavonoid Contents in the Flowers and Leaves of Ghaneri (Lantana camara L.) as Affected by Different Extraction Solven

Farooq Anwar, Nusrat Shaheen, Ghulam Shabir, Muhammad Ashraf, Khalid M. Alkharfy and Anwarul-Hassan Gilani
The current study reports variation in antioxidant activity and phenolic and flavonoid contents in the flowers and leaves of a medicinal herb Ghaneri (Lantana camara L.) as affected by different extraction solvents (80% methanol, 80% ethanol, absolute methanol and absolute ethanol). The antioxidant activity was assessed by measuring the reducing power, inhibition in linoleic acid peroxidation and 2, 2-diphenyl-1-picrylhydrazyl radical (DPPH●) scavenging activity. Of the extracts tested, flower extract produced by 80% methanol possessed maximum amount of total phenolics (21.4 g GAE/100 g DW), total flavonoids (13.8 g CE/100 g DW), reducing power (0.095 for extract concentration of 1.0 mg mL-1), inhibition of linoleic acid peroxidation (83.3%) and DPPH radical scavenging activity (72.3%). A significant difference was observed for phenolic and flavonoid contents and antioxidant activity in relation to different extraction solvents and plant parts analyzed (p<0.05) thus prompting the need for utilization of appropriate solvent media and material for isolation of maximum amount of antioxidants. The results of this study explore the potential of L. camara as a rich source of natural antioxidants for development of functional foods and nutraceutical applications.
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How to cite this article

Farooq Anwar, Nusrat Shaheen, Ghulam Shabir, Muhammad Ashraf, Khalid M. Alkharfy and Anwarul-Hassan Gilani, 2013. Variation in Antioxidant Activity and Phenolic and Flavonoid Contents in the Flowers and Leaves of Ghaneri (Lantana camara L.) as Affected by Different Extraction Solven. International Journal of Pharmacology, 9: 442-453.

DOI: 10.3923/ijp.2013.442.453

URL: https://scialert.net/abstract/?doi=ijp.2013.442.453

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