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International Journal of Pharmacology
  Year: 2012 | Volume: 8 | Issue: 8 | Page No.: 695-700
DOI: 10.3923/ijp.2012.695.700
 
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Influence of Tartary Buckwheat Extracts Supplementation on Oxidative Stress Induced by Acute Exhaustive Exercise in Rats

Yan Fei-Wei, Fang Fang, Jin Hong-Mei and Jin Ye

Abstract:
Tartary Buckwheat Extracts (TBE) has been reported to be a potential antioxidant that may affect health and exercise performance. The objective of this study was to examine the effects of TBE supplementation on oxidative stress induced by acute exhaustive exercise in rats. Male Sprague-Dawley rats were randomly divided into four groups, each consisting of ten rats. The first group designated as control group was administered with distilled water by gavage every day for 28 days. The other three groups designated as TBE supplementation groups were administered with TBE of 60, 120 and 240 mg kg-1 body weight (b.wt.), respectively, by gavage every day for 28 days. After acute exhaustive exercise, the antioxidant enzyme activities and malondialdehyde (MDA) levels were determined. The data showed that TBE at the dose 60, 120 and 240 mg kg-1 b.wt. increased Super Oxide Dismutase (SOD) activities in liver tissue of rats significantly by 28.13, 34.65 and 45.95%, respectively, increased catalase (CAT) activities significantly by 29.49, 41.63 and 59.30%, respectively and decreased MDA levels significantly by 31.21, 51.12 and 45.68%, respectively. TBE at the dose 120 and 240 mg kg-1 b.wt. increased glutathione peroxidase (GPx) activities significantly by 21.33 and 28.22%, respectively. TBE at the dose 240 mg kg-1 b.wt. increased Glutathione Reductase (GR) activities significantly by 31.58%. These results suggested that TBE supplementation has a protective effect on oxidative stress induced by acute exhaustive exercise.
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How to cite this article:

Yan Fei-Wei, Fang Fang, Jin Hong-Mei and Jin Ye, 2012. Influence of Tartary Buckwheat Extracts Supplementation on Oxidative Stress Induced by Acute Exhaustive Exercise in Rats. International Journal of Pharmacology, 8: 695-700.

DOI: 10.3923/ijp.2012.695.700

URL: https://scialert.net/abstract/?doi=ijp.2012.695.700

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