Submit Manuscript

International Journal of Pharmacology

Year: 2011 | Volume: 7 | Issue: 4 | Page No.: 516-521
Facebook Twitter Digg Reddit Linkedin StumbleUpon E-mail

Article Trend

Total views 237

Authors

Mansoor Rastegarpanah

Naghmeh Omidzohour

Homayoon Vahedi

Reza Malekzadeh

Farshad Hashemian

Tahereh Safarnavadeh

Mohammad Abdollahi

Keywords

To evaluate clinical benefit of Satureja Khuzestanica (SK) trade named Saturex in Ulcerative Colitis (UC). A randomized controlled trial was conducted in UC patients. Patients with proliferative retinopathy, significant renal impairment (serum creatinine>3 mg dL-1), documented coronary artery disease, chronic liver disease, diabetic foot ulceration and gangrene and pulmonary infection were excluded from the study. The patients were administered 500 mg SK or placebo supplements once daily while they were maintained on their current treatment for UC. After 4 months, frequency difference of the disease flare up was compared between study and placebo groups. 12/14 (85.5%) of SK patients were in complete remission after 4 months as compared to 6/13 (46.2%) of the patients on placebo. The flare up frequency difference (0.07-0.73) between two groups was significant. Supplementing with SK by preventing disease flare up and keeping the patients in remission state would give the opportunity to physicians to reduce the dose of chemical drugs resulting in lower side effects and better compliance of patients.
PDF Fulltext XML References Citation

How to cite this article

Mansoor Rastegarpanah, Naghmeh Omidzohour, Homayoon Vahedi, Reza Malekzadeh, Farshad Hashemian, Tahereh Safarnavadeh and Mohammad Abdollahi, 2011. Management of Human Ulcerative Colitis by SaturexTM: A Randomized Controlled Trial. International Journal of Pharmacology, 7: 516-521.

DOI: 10.3923/ijp.2011.516.521

URL: https://scialert.net/abstract/?doi=ijp.2011.516.521

Related Articles

An Evidence-based Review on Medicinal Plants used for the Treatment of Peptic Ulcer in Traditional Iranian Medicine
A Comprehensive Review of Biochemical and Molecular Evidences from Animal and Human Studies on the Role of Oxidative Stress in Aging: An Epiphenomenon or the Cause
Hypoglycemic Property of Satureja khuzestanica in Human Still in Doubt
Benefit of Lemon Verbena in Healthy Subjects; Targeting Diseases Associated with Oxidative Stress
Is There a Place for Satureja species in Complementary and Alternative Medicine? Animals Studies Done but Clinical Trials Remain
An Update on Pharmacology of Satureja Species; From Antioxidant, Antimicrobial, Antidiabetes and Anti-hyperlipidemic to Reproductive Stimulation
An Update on Pharmacology of Satureja Species; From Antioxidant, Antimicrobial, Antidiabetes and Anti-hyperlipidemic to Reproductive Stimulation

Leave a Comment

Your email address will not be published. Required fields are marked *