Subscribe Now Subscribe Today
Science Alert
 
Blue
   
Curve Top
International Journal of Pharmacology
  Year: 2010 | Volume: 6 | Issue: 5 | Page No.: 691-695
DOI: 10.3923/ijp.2010.691.695
 
Facebook Twitter Digg Reddit Linkedin StumbleUpon E-mail

A Systematic Review on the Efficacy of Herbal Medicines in the Management of Human Drug-induced Hyperprolactinemia; Potential Sources for the Development of Novel Drugs

S. Hasani- Ranjbar, H. Vahidi, S. Taslimi, N. Karimi, B. Larijani and M. Abdollahi

Abstract:
Several drugs may increase blood prolactin concentration. Dopamine receptor antagonists are one of the most common causes of hyperprolactinemia. To reduce happening of hyperprolactinemia, some medicinal plants have been traditionally used. This review focuses on the efficacy of effective herbal medicines in the management of human drug-induced hyperprolactinemia. PubMed, Scopus, Web of science, Cochrane library database were searched for any relevant studies that investigated the effect of herbal medicines on drug induced hyperprolactinemia up to May 2010. The inclusion criteria were clinical trials studied efficacy of herbal medicines in drug-induced hyperprolactinemia. Among different compounds, four herbal supplements including Shakuyaku-kanzo-to (TJ-68), Peony-Glycyrrhiza Decoction (PGD), Zhuangyang capsule, Tongdatang serial recipe (TDT) were found clinically effective and safe in management of drug-induced hyperprolactinemia. Although, the quality of included clinical trials was low not allowing us to conduct a meta-analysis but positive results on efficacy (TJ-68), (PGD), Zhuangyang capsule and (TDT) cannot be ignored. Interestingly compounds with prolactin-suppressive effects have a number of diterpenes mainly clerodadienols that seem almost identical for their efficacy. Further studies to isolate and characterize constituents of the effective herbs are needed to reach novel therapeutic and more effective agents.
PDF Fulltext XML References Citation Report Citation
 RELATED ARTICLES:
  •    South Asian Herbal Plants as Anti-hypertensive Agents- A Review
  •    Biochemical and Hormonal Effects of Nymphaea lotus Aqueous Extract on Hyperprolactinemic Female Wistar Rats
  •    A Review on the Pharmacological Aspects of Terminalia chebula
  •    Effects of the Mixture of Melissa officinalis L., Cinnamomum zeylanicum and Urtica dioica on Hepatic Enzymes Activity in Patients with Nonalcoholic Fatty Liver Disease
  •    A Systematic Review of the Efficacy and Safety of Teucrium Species; from Anti-oxidant to Anti-diabetic Effects
  •    An Update on Pharmacology of Satureja Species; From Antioxidant, Antimicrobial, Antidiabetes and Anti-hyperlipidemic to Reproductive Stimulation
How to cite this article:

S. Hasani- Ranjbar, H. Vahidi, S. Taslimi, N. Karimi, B. Larijani and M. Abdollahi, 2010. A Systematic Review on the Efficacy of Herbal Medicines in the Management of Human Drug-induced Hyperprolactinemia; Potential Sources for the Development of Novel Drugs. International Journal of Pharmacology, 6: 691-695.

DOI: 10.3923/ijp.2010.691.695

URL: https://scialert.net/abstract/?doi=ijp.2010.691.695

COMMENT ON THIS PAPER
 
 
 

 

 
 
 
 
 
 
 
 
 

 
 
 
 
 
 
 
 
 
 
 

Curve Bottom