
	International Journal of Pharmacology
	Year: 2010 \| Volume: 6 \| Issue: 4 \| Page No.: 510-514 DOI: 10.3923/ijp.2010.510.514

Antimicrobial Activity Evaluation of Cassia spectabilis Leaf Extracts

N. Krishnan, S. Ramanathan, S. Sasidharan, V. Murugaiyah and S.M. Mansor

Abstract: The aim of the present study was to characterize the antimicrobial properties of various crude extracts of the Cassia spectabilis leaf against bacteria and yeast. Acetone, n-hexane, dichloromethane, ethyl acetate and methanol extracts of C. spectabilis leaves were evaluated in vitro against Gram positive bacteria (Bacillus subtilis and Staphylococcus aureus), Gram negative bacteria (Escherichia coli, Salmonella typhi and Pseudomonas aeroginosa) and yeast (Candida albicans). The Minimum Inhibitory Concentration (MIC), Minimum Bactericidal Concentration (MBC) and Minimum Fungicidal Concentration (MFC) were determined using micro dilution assay. Methanol showed the highest yield (14.12%) followed by dichloromethane (8.37%), acetone (6.66%), ethyl acetate (4.76%) and n-hexane (1.80%). Acetone and methanol crude extracts showed a good antimicrobial activity with MIC values ranging from 0.625 to 2.5 mg mL^-1 and MBC or MFC values ranging from 1.25 to 5 mg mL^-1. The MIC, MFC and MBC values of these extracts were 10 to 80 times less potent than standard antimicrobial drugs, amoxilin and miconazole nitrate.

PDF Fulltext XML References Citation Report Citation

RELATED ARTICLES:

•	Evaluation of the Antibacterial Properties of Aqueous and Methanol Extracts of Cassia alata

•	Evaluation of Analgesic and Antioxidant Potency of Various Extracts of Cinnamomum iners Bark

•	Targeting Virulence: Novel Effect of Myristica fragrans on Melanisation and Conidiation of Aspergillus niger

•	Antibacterial Activities of Curcumin Bioconjugates

•	Antimicrobial Activity of Senna spectabilis and S. tora

•	Antibacterial Activity, Bioavailability and Acute Toxicity Evaluation of the Leaf Extract of Alchornea cordifolia (Euphorbiaceae)

•	Antibacterial Effect of Ethanolic and Methanolic Extracts of Plantago ovata and Oliveria decumbens Endemic in Iran Against Some Pathogenic Bacteria

How to cite this article:

N. Krishnan, S. Ramanathan, S. Sasidharan, V. Murugaiyah and S.M. Mansor, 2010. Antimicrobial Activity Evaluation of Cassia spectabilis Leaf Extracts. International Journal of Pharmacology, 6: 510-514.

DOI: 10.3923/ijp.2010.510.514

URL: https://scialert.net/abstract/?doi=ijp.2010.510.514

COMMENT ON THIS PAPER

Navigation


		Online First
		Current Issue
		Previous Issues
		Editorial Board
		Submit a Manuscript
		Guide to Authors
		Subscribe to E-alerts

Indexed In


		ASCI-Database
		Asian Digital Library
		Chemical Abstract Services
		EMBASE
		Google Scholar
		ISI Web of Knowledge
		Science Citation Index (EXP)
		SCIMAGO
		Thomson ISI

Science Alert