Research Article

**The Obtaining of an Antioxidant Product Based on a Rosmarinus officinalis Freeze-Dried Extract**

The aim of this study was to obtain a freeze-dried extract with an important antioxidant and antimicrobial effect from Rosmarinus officinalis. The extracts were obtained in a fluidized bed solid extractor and there has resulted that the optimal values of phenols, flavonoids and the highest reduction power were determined when using 70% ethanol as solvent, the antioxidant activity ranging between 90-95%. In case of the freeze-dried product, the maximum antioxidant activity was registered when using 0.2 mg mL^-1 powder and the results were optimal as well in case of determining flavonoids, phenols and the reduction power. The antimicrobial effect of the extracts and of the freeze-dried product were quantified by using the Colony Quant software on the strains Escherichia coli CBAB 2, Bacillus cereus CMGB 215, Listeria innocua CMGB 218. An inhibition area of maximum 2 cm resulted when using 70% ethanol as solvent. The optimal inhibitory effect of the freeze-dried product, of around 1.8 cm, was determined by a 0.2 mg mL^-1 concentration.

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V. Emanuel, V. Adrian and Nita Sultana, 2010. The Obtaining of an Antioxidant Product Based on a Rosmarinus officinalis Freeze-Dried Extract. International Journal of Pharmacology, 6: 425-430.

DOI: 10.3923/ijp.2010.425.430

URL: https://scialert.net/abstract/?doi=ijp.2010.425.430

International Journal of Pharmacology

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Authors

V. Emanuel

V. Adrian

Nita Sultana

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Research Article

**The Obtaining of an Antioxidant Product Based on a Rosmarinus officinalis Freeze-Dried Extract**

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