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International Journal of Pharmacology
  Year: 2010 | Volume: 6 | Issue: 2 | Page No.: 152-156
DOI: 10.3923/ijp.2010.152.156
 
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Effect of Tecoma stans Leaves on the Reproductive System of Male Albino Rats

Nidhi Mathur, G.C. Jain and Geeta Pandey

Abstract:
Effects of 50% ethanolic extract of Tecoma stans leaves were investigated in adult Wistar male rats. Changes in weight of the liver, kidneys and adrenal of the rats were statistically insignificant (p<0.05). The relative weight of testes, epididymis, vas deferens, ventral prostate and seminal vesicle were decreased significantly (p<0.001). Tecoma stans treatment showed significant high cholesterol, glycogen and low tissue sialic acid and total protein in testes and epididymis and low fructose level in seminal vesicle of treated rats. Hormonal assay showed decrease in testosterone level. The epididymal sperm count, motility and fertility test (%) reduced significantly in treated rats. Histopathological study of the testes depicted marked degenerative changes in testes. The seminiferous tubules appear reduced in size. Vacuolization was observed in the sertoli cells, spermatogonia and spermatocytes. Leydig cells were atrophied. Germ cell proliferation beyond the level of the spermatocyte was affected. The lumen contained sloughed debris and few germ cells.
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How to cite this article:

Nidhi Mathur, G.C. Jain and Geeta Pandey, 2010. Effect of Tecoma stans Leaves on the Reproductive System of Male Albino Rats. International Journal of Pharmacology, 6: 152-156.

DOI: 10.3923/ijp.2010.152.156

URL: https://scialert.net/abstract/?doi=ijp.2010.152.156

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