Subscribe Now Subscribe Today
Science Alert
 
FOLLOW US:     Facebook     Twitter
Blue
   
Curve Top
International Journal of Pharmacology
  Year: 2010 | Volume: 6 | Issue: 2 | Page No.: 129-133
DOI: 10.3923/ijp.2010.129.133
Hypoglycemic and Hypolipidemic Activities of Trianthema portulacastrum Linn. Plant in Normal and Alloxan Induced Diabetic Rats
R.N.R. Anreddy, M. Porika, N.R. Yellu and R.K. Devarakonda

Abstract:
The present study was designed to evaluate the hypoglycemic and hypolipidemic activity of methanol extract of Trianthema portulacastrum Linn. whole plant in normal and alloxan-induced diabetic rats. Alloxan was used to induce diabetes in rats and the blood glucose, lipid levels were estimated using commercial kits available in the market. The methanol extract of T. portulacastrum was administered for 7 days to normal and alloxan induced diabetes rats at a dose of 100, 200 and 300 mg kg-1. The extract produced significant reduction (p<0.001) in blood glucose at a doses of 100, 200 and 300 mg kg-1 in normal and diabetic rats. It also produced beneficial effects on the lipid profile in normal as well as alloxan induced diabetic rats at the end of the treatment period (7th day). The methanol extract of Trianthema portulacastrum produced a dose dependent hypoglycemic, antihyperglycemic and hypolipidemic activity in rats and were comparable with standard oral hypoglycemic agent, glibenclamide.
PDF Fulltext XML References Citation Report Citation
 RELATED ARTICLES:
  •    Beneficial Effect of Aqueous Stem Bark Extracts of Strychnos henningsii Gilg in Streptozotocin-nicotinamide Induced Type 2 Diabetic Wistar Rats
  •    Hypoglycemic and Hypolipidemic Activity of Pongamia pinnata (Linn.) Pierre in Streptozotocin-induced Diabetic Rats
  •    International Journal of Pharmacology 2010: A Tremendous Year and Future Prospects
  •    Management of Type 2 Diabetes Mellitus by Lifestyle, Diet and Medicinal Plants
How to cite this article:

R.N.R. Anreddy, M. Porika, N.R. Yellu and R.K. Devarakonda, 2010. Hypoglycemic and Hypolipidemic Activities of Trianthema portulacastrum Linn. Plant in Normal and Alloxan Induced Diabetic Rats. International Journal of Pharmacology, 6: 129-133.

DOI: 10.3923/ijp.2010.129.133

URL: https://scialert.net/abstract/?doi=ijp.2010.129.133

 
COMMENT ON THIS PAPER
 
 
 

 

 
 
 
 
 
 
 
 
 

 
 
 
 
 
 
 
 
 
 
 

       

       

Curve Bottom