Hypoglycemic and Hypolipidemic Activities of Trianthema portulacastrum Linn. Plant in Normal and Alloxan Induced Diabetic Rats


	International Journal of Pharmacology
	Year: 2010 \| Volume: 6 \| Issue: 2 \| Page No.: 129-133 DOI: 10.3923/ijp.2010.129.133

Hypoglycemic and Hypolipidemic Activities of Trianthema portulacastrum Linn. Plant in Normal and Alloxan Induced Diabetic Rats

R.N.R. Anreddy, M. Porika, N.R. Yellu and R.K. Devarakonda

Abstract: The present study was designed to evaluate the hypoglycemic and hypolipidemic activity of methanol extract of Trianthema portulacastrum Linn. whole plant in normal and alloxan-induced diabetic rats. Alloxan was used to induce diabetes in rats and the blood glucose, lipid levels were estimated using commercial kits available in the market. The methanol extract of T. portulacastrum was administered for 7 days to normal and alloxan induced diabetes rats at a dose of 100, 200 and 300 mg kg^-1. The extract produced significant reduction (p<0.001) in blood glucose at a doses of 100, 200 and 300 mg kg^-1 in normal and diabetic rats. It also produced beneficial effects on the lipid profile in normal as well as alloxan induced diabetic rats at the end of the treatment period (7th day). The methanol extract of Trianthema portulacastrum produced a dose dependent hypoglycemic, antihyperglycemic and hypolipidemic activity in rats and were comparable with standard oral hypoglycemic agent, glibenclamide.

PDF Fulltext XML References Citation Report Citation

RELATED ARTICLES:

•	Beneficial Effect of Aqueous Stem Bark Extracts of Strychnos henningsii Gilg in Streptozotocin-nicotinamide Induced Type 2 Diabetic Wistar Rats

•	Hypoglycemic and Hypolipidemic Activity of Pongamia pinnata (Linn.) Pierre in Streptozotocin-induced Diabetic Rats

•	International Journal of Pharmacology 2010: A Tremendous Year and Future Prospects

•	Management of Type 2 Diabetes Mellitus by Lifestyle, Diet and Medicinal Plants

How to cite this article:

R.N.R. Anreddy, M. Porika, N.R. Yellu and R.K. Devarakonda, 2010. Hypoglycemic and Hypolipidemic Activities of Trianthema portulacastrum Linn. Plant in Normal and Alloxan Induced Diabetic Rats. International Journal of Pharmacology, 6: 129-133.

DOI: 10.3923/ijp.2010.129.133

URL: https://scialert.net/abstract/?doi=ijp.2010.129.133

COMMENT ON THIS PAPER

Navigation


		Online First
		Current Issue
		Previous Issues
		Editorial Board
		Submit a Manuscript
		Guide to Authors
		Subscribe to E-alerts

Indexed In


		ASCI-Database
		Asian Digital Library
		Chemical Abstract Services
		EMBASE
		Google Scholar
		ISI Web of Knowledge
		Science Citation Index (EXP)
		SCIMAGO
		Thomson ISI

Follow @scialert

Science Alert