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International Journal of Pharmacology
  Year: 2007 | Volume: 3 | Issue: 2 | Page No.: 198-200
DOI: 10.3923/ijp.2007.198.200
Biochemical Effects of the Seed Extract of Telfairia occidentalis in Rats
O.A. Eseyin, I. Udoh, A. Ekpo, E.J. Edoho and A.C. Igboasoiyi

Abstract:
Effect of the ethanol extract of seed of Telfairia occidentalis in rat was evaluated. 100, 250, 500 and 1000 mg kg-1 of the extract was orally administered daily to four different groups of Wistar albino rats (127±13 g) for 28 days. The fifth group of rats (i.e., control) received saline water only. On the 29th day blood was collected from the overnight fasted rats through cardiac puncture under chloroform anaesthesia. Appropriate commercial (RandoxR) kits were used to analyze the blood serum for the following enzymes and biomolecules: Aspartatetransaminase (ASAT), alaninetransaminases (ALAT), alkaline phosphatase, total cholesterol, High density lipoproteins (HDL), Triglyceride (TG), creatinine, total proteins, total and conjugated bilirubin and glucose. The extract significantly increased the serum levels of total cholesterol, total proteins, total bilirubin, conjugated bilirubin and glucose; but decreased the levels of HDL.
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How to cite this article:

O.A. Eseyin, I. Udoh, A. Ekpo, E.J. Edoho and A.C. Igboasoiyi, 2007. Biochemical Effects of the Seed Extract of Telfairia occidentalis in Rats. International Journal of Pharmacology, 3: 198-200.

DOI: 10.3923/ijp.2007.198.200

URL: https://scialert.net/abstract/?doi=ijp.2007.198.200

 
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