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International Journal of Pharmacology
  Year: 2007 | Volume: 3 | Issue: 2 | Page No.: 183-186
DOI: 10.3923/ijp.2007.183.186
Propacetamol and Morphine in Postoperative Pain Therapy after Renal Transplantation
Mohammad Reza Khajavi, Atabak Najafi, Mehdi PanahKhahi and Reza Shariat Moharari

Abstract:
The purpose of this study was to assess the analgesic efficacy and complication of intravenous propacetamol, compared with morphine after renal transplantation. In this randomized double blind study, 30 end stage renal disease candidates for renal transplantation from live donors, were divided into two groups: the first group (15 patients) received 2 g of propacetamol (IV), while the other group received 5 mg of morphine (IV). The intensity of pain and the complications were evaluated for 24 h (each 6 h). The mean intensity of pain in the group who received morphine was slightly lower than propacetamol at recovery (10 min after extubation) and 24 h following the operation. However, propacetamol showed significantly less adverse events. The analgesic efficacy of Morphine in controlling post operative pain in time (0) and 24 h following the operation was significantly greater than propacetamol whilst the latter showed less adverse effects during the study period.
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How to cite this article:

Mohammad Reza Khajavi, Atabak Najafi, Mehdi PanahKhahi and Reza Shariat Moharari, 2007. Propacetamol and Morphine in Postoperative Pain Therapy after Renal Transplantation. International Journal of Pharmacology, 3: 183-186.

DOI: 10.3923/ijp.2007.183.186

URL: https://scialert.net/abstract/?doi=ijp.2007.183.186

 
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