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International Journal of Pharmacology
  Year: 2006 | Volume: 2 | Issue: 6 | Page No.: 618-622
DOI: 10.3923/ijp.2006.618.622
 
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The Effects of Ethanolic Leaf Extract of Commiphora africana (Buseraceae) on Lipid Profile in Rats

A.H. Adebayo , R. Aliyu , D. Gatsing and I.H. Garba

Abstract:
The effects of ethanolic leaf extract of Commiphora africana on some serum lipid profiles were investigated in rats. Graded concentrations of 0, 25, 50, 100 and 150 mg kg-1 body weight of the extract were administered by gastric incubations for 24 h, 48 h and 10 days durations. The following lipid profiles were examined in the serum: total cholesterol, high-density lipoprotein (HDL) cholesterol, low-density lipoprotein (LDL) cholesterol and triglycerides. After these durations of treatment there were significant decreases in total cholesterol (p<0.05), triglycerides (p<0.05) and LDL cholesterol (p<0.01), while there was a significant (p<0.01) increase in HDL cholesterol. The result therefore suggests that Commiphora africana ethanolic leaf extract possesses anti-lipidaemic properties and may be used for the management of cardiovascular disorders.
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How to cite this article:

A.H. Adebayo , R. Aliyu , D. Gatsing and I.H. Garba , 2006. The Effects of Ethanolic Leaf Extract of Commiphora africana (Buseraceae) on Lipid Profile in Rats . International Journal of Pharmacology, 2: 618-622.

DOI: 10.3923/ijp.2006.618.622

URL: https://scialert.net/abstract/?doi=ijp.2006.618.622

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