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International Journal of Cancer Research
  Year: 2009 | Volume: 5 | Issue: 2 | Page No.: 53-57
DOI: 10.3923/ijcr.2009.53.57
 
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Pretreatment Serum Squamous Cell Carcinoma Antigen Levels in Esophageal Squamous Cell Carcinoma
F. Homaei-Shandiz, G. Maddah, A. Aledavood, M. Moradi Marjaneh, K. Ghaffarzadehgan, M. Khajedaluee, G. Nowferesti and M.N. Forghani

Abstract:
The present study tried to evaluate pretreatment SCCAg in esophageal squamous cell carcinoma patients in this region. Forty six patients with a biopsy-proven diagnosis of esophageal squamous cell carcinoma were recruited to this study. Tumors were located by endoscopy. The lesions were histologically graded and TNM staging was performed according to the radiologic, clinical and postoperative findings. Pretreatment serum SCCAg levels were measured by RIA and compared with clinicopathological aspects of tumor. The mean pre-treatment SCCAg level was 3.82 ng mL-1 while 21.7% of patients had elevated levels (>3 ng mL-1). Tumor size was the only studied clinicopathologic factor significantly associated with SCCAg. Positive patients had greater tumor size compared to negative ones (p = 0.031). Although, SCCAg marker was positive in minority of the patients, but considering its relation with tumor size and probability disease stage, it is suggested to carry out survival study on more cases to find out the relation between marker positivity and cancer recurrence.
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How to cite this article:

F. Homaei-Shandiz, G. Maddah, A. Aledavood, M. Moradi Marjaneh, K. Ghaffarzadehgan, M. Khajedaluee, G. Nowferesti and M.N. Forghani, 2009. Pretreatment Serum Squamous Cell Carcinoma Antigen Levels in Esophageal Squamous Cell Carcinoma. International Journal of Cancer Research, 5: 53-57.

DOI: 10.3923/ijcr.2009.53.57

URL: https://scialert.net/abstract/?doi=ijcr.2009.53.57

 
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