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International Journal of Cancer Research
  Year: 2005 | Volume: 1 | Issue: 2 | Page No.: 109-112
DOI: 10.3923/ijcr.2005.109.112
 
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Reducing Effect of Strobilanthes crispus Leaf Extract in Hepatocarcinogenesis Rats
O. Fauziah , P. Hanachi , S. Yogespiriya and R. Asmah

Abstract:
The effect of Strobilanthes crispus extract and glycyrrhizin in on rats induced with carcinoma is reported. The results showed significant, increase of liver microsome glutathione s-transferase (GST) in rats after 12 weeks. Treatment with glycyrrhizin caused decrease in liver GST activity compared to control. Treatment with Strobilanthes crispus extract caused overall decrease in liver GST activity almost close to control groups. The microscopic observation of the lesion score during hepatocarcinogenesis revealed that cells of cancer group without treatment were severely necrotic at week 12. However, cells of cancer group with S. crispus treatment appeared normal at the same period.
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How to cite this article:

O. Fauziah , P. Hanachi , S. Yogespiriya and R. Asmah , 2005. Reducing Effect of Strobilanthes crispus Leaf Extract in Hepatocarcinogenesis Rats. International Journal of Cancer Research, 1: 109-112.

DOI: 10.3923/ijcr.2005.109.112

URL: https://scialert.net/abstract/?doi=ijcr.2005.109.112

 
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