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International Journal of Agricultural Research
  Year: 2011 | Volume: 6 | Issue: 3 | Page No.: 290-298
DOI: 10.3923/ijar.2011.290.298
Antihelmentic Effects of the Essential oil Extracts of Selected Medicinal Plants against Haemonchus contortus
Jemal Hussien, Kaba Urgessa, Fayissa Regassa, Awol Jemal, Sultan Abajebel and Nezif Hussien

Abstract:
The present study was aimed at investigating the antihelmentic effects of the essential oil extracts of Coriandrum sativum Linn., Ocimum gratissimum Linn., Ocimum lamifolium Hochst. ex Benth, Ruta chalpensis Linn., Thymus schimperi Ronniger and Echinops kebericho Mesfin against H. contortus. In vitro bioassay employing the egg hatching test was conducted to determine the antihelmentic potential of the essential oils at 1, 0.5, 0.25, 0.125 and 0.0625% (v/v) concentration. The concentration of the extracts that inhibited 50% of test organisms (IC50) was determined using probit analysis of the mean percent egg hatch inhibition followed by linear regression analysis. Accordingly, the plants demonstrated inhibitory effects on hatching of eggs at all concentration levels. The mean percent inhibition at 1% conctration ranged from 81.8±0.6 (E. kebericho) to 100±0 (O. gratissimum and R. chalpensis). At each test concentration of the essential oils, the observed biological effect was statistically significant (p<0.05). Among the extracts, the essential oils of O. gratissimum (IC50 0.0784% v/v), R. chalpensis leaf (IC50 0.0876% v/v) and fruit (IC50 0.0944% v/v) were found to be the most active against H. contortus egg hatching. The intensity of egg hatching inhibitory effect of the essential oils was observed to vary in a dose dependent fashion (p<0.05) and 1% concentration of the essential oils of most of the plants investigated was generally best efficacious with comparable efficacy to the positive antihelmentic compound, thiabendazole (0.5 μg mL-1). The result indicated the potential utility of the plants in the control of egg shedding into the environment to prevent infection of new hosts during grazing. In vivo antihelmentic efficacy and toxicity studies of the plants should be established.
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How to cite this article:

Jemal Hussien, Kaba Urgessa, Fayissa Regassa, Awol Jemal, Sultan Abajebel and Nezif Hussien, 2011. Antihelmentic Effects of the Essential oil Extracts of Selected Medicinal Plants against Haemonchus contortus. International Journal of Agricultural Research, 6: 290-298.

DOI: 10.3923/ijar.2011.290.298

URL: https://scialert.net/abstract/?doi=ijar.2011.290.298

 
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